Use of the design in hospital settings
BLADDER CANCER - Graham Roberts Bladder Cancer
For more information contact firstname.lastname@example.org
RENAL CANCER - Nephron-sparing treatment for small renal masses
For more information contact email@example.com
A group based in the Netherlands led by Prof Lenny Verkooijen have established ten cohorts using the TwiCs approach. Around 80-90% of those patients approached accepting both consent to the cohort and consent to future random selection for new (unnamed) treatments.
Key publications: Verkooijen HM, Roes K, van Gils CH. [Cohort multiple randomized controlled trial: a solution for the evaluation of multiple interventions]. Ned Tijdschr Geneeskd. 2013;157(17):A5762.
PROSPECTIVE NATIONAL COLO-RECTAL CANCER COHORT
This ongoing study is based in the University Medical Center, Utrecht, The Netherlands. The study started life as the ProspectIve data CollectioN Initiative on Colorectal cancer (PICNIC) study - a prospective observational cohort study. This study is now national and has changed its name.
The links to the study protocol can be found here or here
For more information contact: firstname.lastname@example.org
UMBRELLA – Breast Cancer
Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion'
This ongoing study is based in the Department of Radiotherapy, University Medical Center in Utrecht, The Netherlands
The link to the study protocol can be found here
For more information contact: D.A.YoungAfat@umcutrecht.nl,
PRESENT – Bone metastases
This ongoing study is based at the University Medical Centre in Untrech.
For more information contact: J.M.vanderVelden@umcutrecht.nl
OPTIMISING BRAIN HEALTH IN HIV
This study aims to provide a better understanding of the relationship between cognitive complaints, depression and HIV, and to facilitate trials of interventions to imprvoe brain health in HIV
The protocol for the study can be found here.
The trials nested within this cohort are registered as Clinicaltrials.gov NCT02571504 and NCT02571595
For mroe information contact: Nancy E Mayo
BEHAVIOURAL INTERVENTIONS FOR LOW BACK PAIN PATIENTS WHO ARE OBESE OR OVERWEIGHT
This study aims to determine if a telephone based lifestyle behavioural intervention is effective in reducing pain intensity in overweight or obese patients with low back pain, compared to usual care.
The study protocol was published here. The protocol for a causal mediation analysis of two trials in the project is here
The Finnish Degenerative Meniscal Lesion Study (FIDELITY) trial is a multi centre trial which aims to determine whether arthroscopic partial meniscectomy of patients with degenerative meniscus injury is improved by a number of different types of surgery.
For further information contact: email@example.com