Welcome to the TwiCs network where we share information about the Trials within Cohorts (TwiCs) approach for designing and conducting practical randomised controlled trials.
Trials within Cohorts (TwiCs) approach uses infrastructures (cohorts) to facilitate the conduct of multiple randomised controlled trials.
See COVIDENCE for a recent example of this approach to tackle questions related to the management of COVID-19 in the UK.
CONSORT REPORTING GUIDELINES accepted for publication in the BMJ
Extension to Improve Reporting of Trials Using Observational Cohorts, Registries and Routinely Collected Health Data
(Funded by the Canadian Institutes of Health Research and the UK NIHR Clinical Trials Unit Support Funding)